For those averse to injections: The world's first and only GLP-1 tablet for medical weight loss.
If you're interested in medical weight loss but have been hesitant about self-injection, Rybelsus® is the treatment option designed for you. As an oral GLP-1 receptor agonist, it helps you control your appetite and supports healthy weight loss with the simple habit of taking one tablet each day. This allows anyone who was held back by a fear of needles to confidently begin their treatment journey.
Just One Tablet, Once a Day
Absolutely no injections are required. This simple, once-daily pill is easy to incorporate into your morning routine, removing the physical and mental stress associated with shots.
Natural Appetite Suppression
This medication works by targeting the hypothalamus in the brain to prolong the feeling of fullness (satiety). This leads to a natural reduction in food intake, supporting a more comfortable and less stressful diet.
Scientifically Proven Effectiveness
Thanks to a proprietary absorption-enhancing technology, this is a revolutionary medication that makes it possible to take a GLP-1 treatment orally—a treatment that was previously only available via injection.
Rybelsus® is recommended for:
- For those who are hesitant about or averse to self-injection.
- For those who prefer a simple, once-daily tablet to stay on track with their treatment.
- For individuals who are new to medical weight loss.
- For those who find intense exercise or strict diets difficult to maintain.
- For those who want to begin their weight loss journey safely with medical supervision.
What is Rybelsus®? - Its Mechanism and Effects
Mechanism of Action
Rybelsus® (generic name: Semaglutide) is a medication that mimics the function of the hormone "GLP-1," which is naturally released from the small intestine after eating. It helps reduce hunger by acting on the brain's appetite centers to increase feelings of fullness and by slowing down how quickly your stomach empties.
Normally, GLP-1 as a protein would be broken down by stomach acid. However, Rybelsus® uses a unique technology with an absorption enhancer (SNAC) that protects the medication and allows it to be effectively absorbed in the stomach as an oral tablet.
Expected Effects
- Gentle Appetite Suppression: Helps you naturally control your food intake without feeling overly restrictive.
- Weight Loss: Continuous weight loss can be expected as a result of reduced caloric intake.
- Blood Sugar Stabilization: Helps moderate the rise in blood sugar levels after meals, guiding your body toward a state where it is less likely to store fat.
How to Take Rybelsus® (Important for Maximum Effectiveness)
To ensure the medication is properly absorbed and to maximize its effectiveness, it is crucial to follow these rules precisely.
- Timing: Take one tablet upon waking, on an empty stomach, before your first food or drink of the day.
- How to Take: Swallow one tablet whole with a small amount of water (no more than 120ml / 4 oz). Do not crush, split, or chew the tablet.
- After Taking: Wait at least 30 minutes after your dose before eating, drinking, or taking any other oral medications.
*Failure to follow these instructions may significantly reduce the absorption and effectiveness of the medication. Always follow your doctor's guidance.
Side Effects and Important Precautions
Side Effects
The following gastrointestinal symptoms may occur, especially at the beginning of treatment. In most cases, these will lessen as you continue the medication.
- Nausea, vomiting
- Diarrhea, constipation
- Stomach discomfort, heartburn
*If you experience persistent or concerning symptoms, please consult your doctor promptly.
Who Cannot Use This (Contraindications)
- Individuals with a history of hypersensitivity to any of Rybelsus's components.
- Individuals with diabetic ketoacidosis, diabetic coma or precoma, or Type 1 diabetes.
- Individuals with severe infections or in cases of emergency such as major surgery.
- Individuals who are pregnant or breastfeeding.
- Individuals with a personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Individuals with a history of pancreatitis.
Pricing
We are committed to transparent pricing so you can continue your treatment with confidence and peace of mind.
*Please note: All prices listed below are for private medical services and are not covered by health insurance.
| What's Included | Price (per month, incl. tax) | Details |
| Rybelsus Oral Plan (3mg) | 6,980 yen | Rybelsus® (3mg) x 30, Shipping, Online Medical Consultation |
| Rybelsus Oral Plan (7mg) | 16,280 yen | Rybelsus® (7mg) x 30, Shipping, Online Medical Consultation |
| Rybelsus Oral Plan (14mg) | 24,420 yen | Rybelsus® (14mg) x 30, Shipping, Online Medical Consultation |
*Your doctor will provide full details during your online consultation.
Frequently Asked Questions (FAQ)
Q. Why are the instructions for timing and water intake so specific?
A. These specific instructions are crucial for the medication's absorption enhancer, SNAC, to work effectively. If taken with too much water, or with food in your stomach, the absorption of Rybelsus® will be significantly reduced, and you may not get the desired therapeutic effect.
Q. What should I do if I miss a dose?
A. If you miss a dose, simply skip it for that day and take your next dose as scheduled the following morning. Do not take two tablets at once to make up for a missed dose.
Q. What is the difference between Rybelsus and Mounjaro® (the injectable)?
A. The primary difference is their mechanism. Mounjaro is a dual-agonist that acts on two receptors (GIP and GLP-1), while Rybelsus is a single-agonist that acts on one (GLP-1). Due to this, Mounjaro generally demonstrates a more significant weight loss effect. Rybelsus, however, has the major advantage of being a daily oral tablet, making it an excellent choice for those who dislike injections. Your doctor will help you determine the most suitable option for you.
Book Your Consultation
For anyone who has been held back by a fear of injections:
Isn't it time to start your journey to a new you, with a medical weight loss program that's as simple as taking a pill?
Our specialist doctors are committed to supporting you until you achieve your goals.
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