Your first step into medical wellness, beginning with gentle glucose management.
Metformin is a highly reliable medication with a trusted history of more than 60 years of use across the globe. Instead of focusing on drastic weight loss, it works by supporting a gentler absorption of sugars, which helps make it harder for your body to gain weight. This makes it a solid foundation for your wellness journey, whether as a first step into medical dieting or used in combination with GLP-1 agonists for enhanced support.
One of the world's most widely used and trusted medications, with a history spanning more than 60 years.
Gentle Carbohydrate Absorption Support
It moderates the absorption of sugar from meals, suppresses glucose production in the liver, and helps prevent blood sugar spikes and excessive insulin secretion.
Weight Gain Suppression & Maintenance
Instead of causing significant weight loss, the primary feature of this treatment is to help your body become more resistant to weight gain. This makes it an ideal option for preventing weight regain (the "rebound" effect) and for those who wish to maintain their current weight.
An Accessible & Affordable Option
As a generic medication with a long and trusted history, Metformin is a highly cost-effective option compared to other medical weight loss treatments. This lower price point is a key advantage, making it a sustainable choice for long-term use.
Metformin is recommended for:
- For those who want to try medical weight management for the first time at an accessible price point.
- For individuals whose diet is rich in carbohydrates (like rice, bread, and pasta).
- For those aiming to build a body more resistant to weight regain, rather than focusing on rapid weight loss.
- For those looking to achieve enhanced synergistic effects through combination therapy with Mounjaro® or Rybelsus®.
- For those interested in long-term health maintenance and potential anti-aging benefits.
What is Metformin? - Its Mechanism and Effects
Mechanism of Action
Metformin is a medication classified as a biguanide, and it works through three primary mechanisms:
- Suppresses glucose production in the liver: It reduces the amount of sugar your liver makes.
- Improves insulin sensitivity: It helps your muscles and other tissues use insulin more effectively, promoting glucose utilization.
- Moderates glucose absorption: It gently slows down the absorption of sugar from your intestines.
Expected Effects and New Possibilities
- Weight Gain Suppression & Mild Weight Loss: Through the actions above, it guides your body toward a state where it is less prone to weight gain.
- Blood Sugar Stabilization: Its long history as a leading diabetes treatment proves its effectiveness in this area.
- Potential for Anti-aging Care: In recent years, it has been discovered that Metformin activates "AMPK," an energy sensor within cells. As a result, it is being studied worldwide for its potential role in extending healthspan (anti-aging).
Usage and Dosage
Typically, treatment starts at 500mg per day, taken in 2-3 divided doses after meals.
To minimize potential gastrointestinal side effects, treatment begins with a low dose, which your doctor will gradually adjust while monitoring your condition. Always follow your doctor's instructions.
Side Effects and Important Precautions
Side Effects
The following gastrointestinal symptoms may occur, especially at the beginning of treatment. They often improve by starting with a low dose and allowing your body to gradually acclimate.
- Diarrhea, constipation
- Nausea, loss of appetite
- Abdominal pain, bloating
*If you experience persistent or concerning symptoms, please consult your doctor promptly.
【Important】About Lactic Acidosis
Although extremely rare (less than 0.008%), a serious side effect called lactic acidosis can occur. This is a condition where lactic acid builds up in the body. If you experience initial symptoms such as nausea, abdominal pain, diarrhea, muscle pain, or excessive drowsiness, stop taking the medication immediately and seek medical attention.
*The risk is higher for individuals with dehydration, excessive alcohol consumption, or impaired kidney/liver function. Your doctor will carefully assess your suitability before prescribing.
Who Cannot Use This (Contraindications)
- Individuals with a history of hypersensitivity to Metformin's components.
- Individuals with severe kidney or liver impairment.
- Individuals with dehydration or severe cardiovascular or pulmonary dysfunction.
- Individuals with excessive alcohol intake.
- Individuals who are pregnant or breastfeeding.
Pricing
We are committed to transparent pricing so you can continue your treatment with confidence and peace of mind.
*Please note: All prices listed below are for private medical services and are not covered by health insurance.
| What's Included | Price (per month, incl. tax) | Details |
| Metformin Plan (500mg, 2 tablets per day) | 1,980 yen | Metformin (500mg, 60 tablets), Online Medical Consultation |
*Your doctor will provide full details during your online consultation.
The Role of Metformin in Our Program
Given its unique characteristics, Metformin can be utilized in our program in two ways:
1. As a Starter Plan Ideal for those who are new to medical weight management and wish to start with an option that is gentle on the body and affordable. With its mild action, it provides a supportive first step into your wellness journey.
2. As a Combination Plan Because its mechanism of action differs from GLP-1 agonists like Mounjaro® and Rybelsus®, a synergistic effect can be expected when used in combination. By adding Metformin's carbohydrate-management benefits to the powerful appetite suppression of a GLP-1, it is possible to achieve more efficient weight management. (Please note: All combination therapy is based on the doctor's clinical judgment.)
Frequently Asked Questions (FAQ)
Q. Will I lose a lot of weight with Metformin alone?
A. Significant weight loss from Metformin alone is not typically expected. Its primary effects are the suppression of weight gain and mild weight loss. It is most suitable for individuals who wish to maintain their current weight or prevent rebound weight gain.
Q. I'm worried about lactic acidosis.
A. Lactic acidosis is an extremely rare side effect. As long as a healthy individual takes the medication as prescribed by a doctor, there is no need for excessive worry. During your online consultation, the doctor will thoroughly check for any kidney or liver issues and lifestyle factors to determine if it is safe for you.
Q. When is the most effective time to take it?
A. To help control the rise in blood sugar after meals, it is generally taken just before or after eating. Please follow the specific instructions provided by your doctor.
Book Your Consultation
Medical wellness is more accessible than ever.
Why not update your health habits with Metformin, a medication trusted worldwide for its proven track record?
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