Next-Generation Regenerative Induction.
High Purity, High Activity Pure Stem Human Umbilical Cord Blood-Derived Exosomes.

Exosome therapy is an innovative treatment method attracting attention as cutting-edge regenerative medicine.
Exosomes are important messengers secreted from stem cells, promoting tissue repair and regeneration through intercellular communication.
Their excellent anti-aging effects contribute to skin rejuvenation, muscle strengthening, and even improved immune function.
The exosomes we provide boast a high purity of over 99% and support health and beauty from the inside out by maximizing the body's regenerative potential.

Experience the future of care today.

With over 99% high purity, containing approximately 7.58 billion exosomes per 0.5ml vial

What are Pure Stem Human Umbilical Cord Blood-Derived Exosomes?

Pure Stem Human Umbilical Cord Blood-Derived Exosomes are an exosome product obtained by culturing carefully selected human umbilical cord blood-derived stem cells and utilizing proprietary high-purity extraction technology.
Exosomes are intercellular messengers that play an important role in tissue repair and functional regulation by delivering microRNA, messenger RNA, and proteins (such as growth factors/cytokines) contained within them to target cells.  

Advantage of Umbilical Cord Blood Origin:
Stem cells contained in umbilical cord blood are younger and more active compared to adult stem cells, and produce more growth factors. As a result, powerful anti-aging effects, tissue repair capabilities, and immune-modulating functions are expected.  

Expected Applications:
By introducing them into the body through methods such as IV drip or local administration, they are expected to contribute to beauty (aging care, skin improvement, hair regeneration), health maintenance (fatigue recovery, immunity enhancement), and support for improving specific conditions (cognitive function, allergic diseases, post-operative recovery, etc.), through the promotion of angiogenesis, anti-inflammatory effects, tissue repair, and more.

Pure Stem Exosome Features

High Purity, High Concentration "Umbilical Cord Blood-Derived" Exosomes
  • Through pure culture, without using any other raw materials, and proprietary recovery technology, we have achieved a purity of over 99%.
  • Each 0.5ml vial contains approximately 7.58 billion exosomes.
  • Compared to exosomes derived from fat or bone marrow, it contains approximately 14 times more active ingredients (cytokines, etc.) related to anti-aging and skin regeneration.
  • Notably, GDF-11, known as the "youth protein", has confirmed expression levels up to 120 times higher compared to fat and bone marrow stem cells, and up to 60 times higher compared to the culture medium.
Compared to those derived from fat or bone marrow, contains approximately 14 times more active ingredients (cytokines, etc.) related to anti-aging and skin regeneration.
Abundant Cytokines (Growth Factors) and Their Functions

Containing dozens of types of active ingredients, it provides multifaceted support for tissue repair and cell activation.

Major Contained Cytokines and Their Expected Effects

  • PDGF (Platelet-Derived Growth Factor):
    Promotes the division of stem cells involved in tissue repair.
  • FGF (Fibroblast Growth Factor):
    Stimulates and proliferates fibroblasts, contributing to wound healing, wrinkle improvement, and whitening effects.  
  • TGF (Transforming Growth Factor):
    An essential factor for producing collagen and elastin; enhances collagen/elastin structure, improves skin moisture and elasticity.  
  • HGF (Hepatocyte Growth Factor):
    Involved in tissue regeneration, including cell proliferation, cell motility, and angiogenesis.  
  • VEGF (Vascular Endothelial Growth Factor):
    Promotes angiogenesis.  
  • KGF (Keratinocyte Growth Factor):
    Acts on hair matrix stem cells to promote hair growth and regrowth.  
  • EGF (Epidermal Growth Factor):
    Promotes skin turnover, improving spots and dullness.  
  • GDF11 (Growth Differentiation Factor 11):
    Promotes skin regeneration and firmness through fibroblast proliferation and increased collagen/elastin. Clinical data suggests it can increase fibroblast regenerative capacity by up to 150%, Collagen type I by up to 5 times, Collagen type III by up to 3 times, and Elastin by up to 50 times. Furthermore, treatment with Pure Stem exosomes has been confirmed to increase Collagen type I synthesis by approximately 143% and Collagen type III synthesis by approximately 67%.  
GDF-11 has expression levels up to 120 times higher compared to fat and bone marrow stem cells, and up to 60 times higher compared to the culture medium.

High Efficacy and Skin Regenerative Capacity
  • Due to the abundant contained growth factors, it promotes fibroblast migration (movement), and strong skin regeneration effects can be expected (with a fibroblast migration rate 1.8 times that of the control group).
  • By activating fibroblasts whose function has declined due to aging and promoting the production of collagen, elastin, and hyaluronic acid, it addresses the root causes of skin aging such as wrinkles, sagging, and loss of firmness.  
Proprietary Freeze-Drying Technology
  • This is a proprietary technology for providing the product with high quality and high purity while maintaining the activity of its active ingredients.
  • By removing moisture to the utmost limit, denaturation caused by heat is minimized.
  • Transport and storage are possible in environments up to 40°C, reducing the hassle of conventional frozen or refrigerated management.
Thorough Safety Management

We have established a strict quality control system covering everything from donor selection to the manufacturing process.

  • Virus-Free Certification:
    At each stage involving donors, umbilical cord blood, stem cells, and culture medium, tests for viruses such as Hepatitis B/C (HBV/HCV), HIV, HTLV, Parvovirus B19, Cytomegalovirus (CMV), and EB virus, as well as mycoplasma and adventitious virus negativity tests, are conducted, and all have been confirmed negative (compliant). Certificates can be provided upon request.  
  • Safety Data Sheet (SDS):
    This is a highly safe product, not classified under GHS. An SDS is available, allowing you to confirm the details.  
  • Raw Material Standards:
    The product is manufactured under consistent quality control.

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  • We provide detailed product information and the latest data not available on the website.
  • You can directly ask our expert staff about and resolve any questions or concerns regarding implementation costs and operation.

Key Differentiators from General Products

  • Origin:
    Limited to young and highly active "Umbilical Cord Blood" origin.  
  • Purity:
    Over 99% high purity achieved through proprietary extraction technology.  
  • Ingredients:
    Contains abundant cytokines, especially a high concentration of GDF-11, compared to fat or bone marrow-derived sources.  
  • Quality Retention:
    Proprietary freeze-drying technology maintains activity while enabling management near room temperature.  
  • Safety:
    Thorough virus testing and traceability.  

Other Selling Points

  • Made in Japan:
    Reliable and trusted domestic manufacturing.  
  • Wide Application Potential:
    Expected use in diverse fields such as cosmetic medicine, anti-aging care, health promotion, and hair treatment.  
  • Evidence-Based Design:
    Product development is based on scientific data, including cytokine content and cell migration ability.  
  • Ease of Handling:
    Freeze-drying simplifies use after reconstitution and reduces the burden of storage and transport.  

Made in Japan

Product information

Product Name: Pure Stem Exosomes [Umbilical Cord]

Contents: 0.5ml / vial  

INCI Name: Human cord blood derived stem cell Exosomes  

Japanese Cosmetic Ingredient Name: Human Umbilical Cord Blood-Derived Stem Cell Exosomes  

Country of Manufacture: Japan  

Storage Method: Store in a cool, dark place (below 25°C recommended); use promptly after reconstitution. The freeze-dried state can tolerate temperatures up to 40°C.  

Other: Safety Data Sheet (SDS) and Virus-Free Certificate are available. Please inquire for details.  

Disclaimer: This product is a raw material intended for research use by medical institutions. It is not intended for diagnosis, treatment, or prevention. The stated effects and efficacy are based on general research concerning exosomes and data related to the ingredients contained in this product, and do not guarantee the effects of the product itself.

▶ Get a plan tailored to your clinic - Start with a free consultation

  • We provide detailed product information and the latest data not available on the website.
  • You can directly ask our expert staff about and resolve any questions or concerns regarding implementation costs and operation.

Frequently Asked Questions (FAQ)

Answering Your Questions About Exosome Therapy!

Q: What is exosome therapy?
A: Exosome therapy is a treatment that uses tiny messengers secreted by stem cells to promote cell repair, regeneration, and rejuvenation. These powerful particles deliver growth factors and important signals to cells, leading to improved skin health, increased energy, and overall wellness.

Q: What makes your exosome therapy different?
A: Our exosome therapy uses stem cells derived from umbilical cord blood, boasting over 99% purity and 14 times more anti-aging growth factors than other sources. Utilizing cutting-edge Japanese technology, we offer unique transformative effects.  

Q: What are the main benefits of exosome therapy?
A:

  • Youthful radiance through improved skin elasticity and reduced wrinkles  
  • Increased energy and faster recovery  
  • Enhanced immune function and reduced inflammation  
  • Hair regeneration and healthier scalp  
  • Improved blood circulation and vascular health  

Q: Is exosome therapy safe?
A: Yes! Our product is developed under strict international standards, ensuring safety, purity, and efficacy. Every batch undergoes thorough testing, so you can use it with confidence.  

Q: How long does it take to see effects?
A: Many people notice improvements in their skin, energy levels, and overall health within a few weeks of starting treatment. Individual results may vary.

Q: How is the product stored and shipped?
A: Thanks to innovative freeze-drying technology, our exosome therapy maintains high quality and purity during storage and shipping. It can be safely managed in environments up to 40°C.  

Q: Who can benefit from exosome therapy?
A: It is ideal for those seeking skin rejuvenation, increased energy, enhanced recovery, and overall wellness. We recommend it for anyone looking to become a better version of themselves.

Do you have more questions? Please feel free to contact us. We are here to support your journey to health and beauty with exosome therapy!

▶ Get a plan tailored to your clinic - Start with a free consultation

  • We provide detailed product information and the latest data not available on the website.
  • You can directly ask our expert staff about and resolve any questions or concerns regarding implementation costs and operation.

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